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Unconventional ways to travel

Nature Cell Biology volume 4, pages E211–E212 (2002)Cite this article

Recent studies of border cells in the Drosophila melanogaster ovary have identified a novel mechanism that is involved in cell migration. Binding of the minus-end-directed motor, Myosin VI, to the cell adhesion molecule, DE-Cadherin, stabilizes the cadherin–catenin complex. This interaction might promote the formation of long cellular extensions (LCEs) at the leading edge of migrating border cells.

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Figure 1: Long cellular extensions in migrating border cells.

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Authors and Affiliations

  1. Department of Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, 02115, MA, USA

    Markus Schober

  2. Department of Genetics and the Howard Hughes Medical Institute, Harvard Medical School, 200 Longwood Avenue, Boston, 02115, MA, USA

    Norbert Perrimon

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  1. Markus Schober
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  2. Norbert Perrimon
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Schober, M., Perrimon, N. Unconventional ways to travel. Nat Cell Biol 4, E211–E212 (2002). https://doi.org/10.1038/ncb0902-e211

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