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The plasma membrane brings autophagosomes to life

Nature Cell Biology volume 12, pages 735–737 (2010)Cite this article

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The plasma membrane is identified as a source for the formation of autophagosomes, the double membrane vesicles that deliver intracellular components to lysosomes for their degradation.

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Figure 1: Autophagosomes originate from the membrane of different organelles.
Figure 2: Formation of autophagosomes out of the plasma membrane requires components of the endocytic machinery.

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Authors and Affiliations

  1. Ana Maria Cuervo is in the Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. ana-maria.cuervo@einstein.yu.edu,

    Ana Maria Cuervo

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  1. Ana Maria Cuervo
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The author declares no competing financial interests.

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Cuervo, A. The plasma membrane brings autophagosomes to life. Nat Cell Biol 12, 735–737 (2010). https://doi.org/10.1038/ncb0810-735

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