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A metabolic assembly line in bacteria

Nature Cell Biology volume 12, pages 731–733 (2010)Cite this article

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The bacterial cytoplasm is rich in filament-forming proteins, from homologues of eukaryotic cytoskeletal elements to other scaffolding and segregation proteins. We now learn that even the metabolic enzyme CTP synthase forms cytoplasmic filaments that affect bacterial cell shape.

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Figure 1: The recent increase in knowledge about filamentous structures in the cytoplasm of walled bacteria.
Figure 2: Possible purposes of CTP synthase polymerization.

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Authors and Affiliations

  1. Department of Molecular, Matthew T. Cabeen is at Yale University, Cellular & Developmental Biology, New Haven, CT 06511, USA.,

    Matthew T. Cabeen

  2. Department of Molecular, Christine Jacobs Wagner is an HHMI Investigator at Yale University, Cellular & Developmental Biology and at Yale University School of Medicine, Microbial Pathogenesis Section, New Haven, CT 06511, USA.,

    Christine Jacobs-Wagner

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  1. Matthew T. Cabeen
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  2. Christine Jacobs-Wagner
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Correspondence to Christine Jacobs-Wagner.

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Cabeen, M., Jacobs-Wagner, C. A metabolic assembly line in bacteria. Nat Cell Biol 12, 731–733 (2010). https://doi.org/10.1038/ncb0810-731

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