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New dimensions in cell migration

Cell migration research is taking some intriguing new turns. Emerging studies are revealing marked differences in the way that cells migrate in two versus three dimensions, plasticity in their migration mechanisms and diversity in the contribution of different Rho family GTPases that drive various modes of migration.

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Figure 1: Modes of cell migration in 3D matrices.

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Webb, D., Horwitz, A. New dimensions in cell migration. Nat Cell Biol 5, 690–692 (2003). https://doi.org/10.1038/ncb0803-690

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