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Stress fibres take shape

Abstract

The GTPase Rho is well known for its ability to induce the assembly of stress fibres. Two interacting targets of Rho, ROCK and Dia1, have been found to act in concert to mediate this response to Rho.

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Figure 1: A model for how ROCK and Dia1 cooperate to mediate Rho-induced stress-fibre formation.

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Correspondence to Anne J. Ridley.

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Ridley, A. Stress fibres take shape. Nat Cell Biol 1, E64–E66 (1999). https://doi.org/10.1038/11034

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