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Protein oxidation: prime suspect found ‘not guilty’

Abstract

Glutathione has long been suspected to be the primary source of oxidative power for protein folding. It has now been shown to be just the opposite, namely a source of reductants. The ultimate origin of oxidants has become even more of a mystery.

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Figure 1: Crime scene: endoplasmic reticulum (ER).

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Correspondence to James C. A. Bardwell.

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Bader, M., Winther, J. & Bardwell, J. Protein oxidation: prime suspect found ‘not guilty’. Nat Cell Biol 1, E57–E58 (1999). https://doi.org/10.1038/11025

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