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Hold on tightly, let go lightly: myosin functions at adherens junctions

Adherens junctions, the sites of cadherin-dependent cell–cell adhesion, are also important for dynamic tension sensing, force transduction and signalling. Different myosin motors contribute to adherens junction assembly and versatility in distinct ways.

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Figure 1: Adherens junctions may be functionally analogous to the kinetochore–sister chromatid complex.


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Sandquist, J., Bement, W. Hold on tightly, let go lightly: myosin functions at adherens junctions. Nat Cell Biol 12, 633–635 (2010).

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