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Cavin fever: regulating caveolae

SDPR is a new regulator of caveolae biogenesis. SDPR overexpression results in increased caveolae size and leads to the formation of caveolae-derived tubules containing Shiga toxin. SDPR may therefore be a membrane curvature-inducing component of caveolae.

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Figure 1: Regulation of caveolae morphology and dynamics by cavin family members.

References

  1. Parton, R. G. & Simons, K. Nature Rev. Mol. Cell Biol. 8, 185–194 (2007).

    Article  CAS  Google Scholar 

  2. Hill, M. M. et al. Cell 132, 113–124 (2008).

    Article  CAS  Google Scholar 

  3. Liu, L. et al. Cell Metabolism 8, 310–317 (2008).

    Article  Google Scholar 

  4. Hansen, C., Bright, N., Howard, G. & Nichols, B. Nature Cell Biol. 11, 807–814 (2009).

    Article  CAS  Google Scholar 

  5. Mineo, C., Ying, Y. S., Chapline, C., Jaken, S. & Anderson, R. G. J. Cell Biol. 141, 601–610 (1998).

    Article  CAS  Google Scholar 

  6. McMahon, K.-A. et al. EMBO J. 28, 1001–1015 (2009).

    Article  CAS  Google Scholar 

  7. Ogata, T. et al. Mol. Cell. Biol. 28, 3424–3436 (2008).

    Article  CAS  Google Scholar 

  8. Tagawa, M. et al. Am. J. Physiol. Cell Physiol. 295, C490–498 (2008).

    Article  CAS  Google Scholar 

  9. Head, B. P. & Insel, P. A. Trends Cell Biol. 17, 51–57 (2007).

    Article  CAS  Google Scholar 

  10. Lajoie, P. et al. J. Cell Biol. 179, 341–356 (2007).

    Article  CAS  Google Scholar 

  11. Lajoie, P., Goetz, J. G., Dennis, J. W. & Nabi, I. R. J. Cell Biol. 185, 381–385 (2009).

    Article  CAS  Google Scholar 

  12. Joshi, B. et al. Cancer Res. 68, 8210–8220 (2008).

    Article  CAS  Google Scholar 

  13. Goetz, J. G., Lajoie, P., Wiseman, S. M. & Nabi, I. R. Cancer Metastasis Rev. 27, 715–735 (2008).

    Article  CAS  Google Scholar 

  14. Kirkham, M. et al. J. Cell Biol. 168, 465–476 (2005).

    Article  CAS  Google Scholar 

  15. Damm, E. M. et al. J. Cell Biol. 168, 477–488 (2005).

    Article  CAS  Google Scholar 

  16. Romer, W. et al. Nature 450, 670–675 (2007).

    Article  Google Scholar 

  17. Lajoie, P. & Nabi, I. R. J. Cell. Mol. Med. 11, 644–653 (2007).

    Article  CAS  Google Scholar 

  18. Richter, T. et al. Traffic 9, 893–909 (2008).

    Article  CAS  Google Scholar 

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Nabi, I. Cavin fever: regulating caveolae. Nat Cell Biol 11, 789–791 (2009). https://doi.org/10.1038/ncb0709-789

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