TACCing down the spindle poles

Centrosomes define the poles of mitotic spindles, but spindles that lack centrosomes mediate meiotic chromosome segregation in females. Recent studies provide new insight into anastral-spindle assembly, and indicate that a conserved protein complex may be critical to the stability of both the astral- and anastral-spindle pole.

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Figure 1: Assembly of an anastral-spindle pole.

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