Abstract
The intermembrane space of mitochondria is home to several potentially lethal proteins, including pro-apoptotic caspases. The observation that caspase-9 moves from mitochondria into the nucleus on the induction of apoptosis provides this caspase with a possible new role.
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References
Li, P. et al. Cell 91, 479–489 (1997).
Susin, S. A. et al. J. Exp. Med. 189, 381– 394 (1999).
Susin, S. A. et al. Nature 397, 441–446 (1999).
Krajewski, S. et al. Proc. Natl Acad. Sci. USA 96, 5752– 5757 (1999).
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T. & Alnemri, E. S. Mol. Cell 1, 949–957 ( 1998).
Kuida, K. et al. Cell 94, 325–337 (1998).
Hakem, R. et al. Cell 94, 339–352 (1998).
Luo, X., Budihardjo, I., Zou, H., Slaughter, C. & Wang, X. Cell 94, 481– 490 (1998).
Li, H., Zhu, H., Xu, C.-J. & Yuan, J. Cell 94, 491–501 (1998).
Cecconi, F., Alvarez-Bolado, G., Meyer, B. I., Roth, K. A. & Gruss, P. Cell 94, 727 –737 (1998).
Yoshida, H. et al. Cell 94, 739–750 (1998).
Soengas, M. S. et al. Science 284, 156–159 (1999).
Saleh, A., Srinivasula, S. M., Acharya, S., Fishel, R. & Alnemri, E. J. Biol. Chem.he press).
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Alnemri, E. Hidden powers of the mitochondria. Nat Cell Biol 1, E40–E42 (1999). https://doi.org/10.1038/10034
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DOI: https://doi.org/10.1038/10034