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Extending the court for cortactin: from the cortex to the Golgi

Vesicle formation at the trans-Golgi network may be mechanistically more similar to endocytic vesicle formation at the plasma membrane than previously thought. Both processes share common components including the dynamin-binding protein cortactin.

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Figure 1: Proposed function for cortactin in actin-supported vesicle formation at the plasma membrane and the TGN.

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Kessels, M., Qualmann, B. Extending the court for cortactin: from the cortex to the Golgi. Nat Cell Biol 7, 448–449 (2005). https://doi.org/10.1038/ncb0505-448

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