Conditional knockout of the KAP3 subunit from the kinesin motor KIF3 alters tissue patterning and causes abnormal proliferation of neural progenitor cells in the mouse brain. Impaired transport of N-cadherin to the surface of these cells may be one explanation for how such defects arise.
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Gottardi, C., den Elzen, N. & Yap, A. When domestiques rebel: kinesins, cadherins and neuronal proliferation. Nat Cell Biol 7, 445–447 (2005). https://doi.org/10.1038/ncb0505-445
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DOI: https://doi.org/10.1038/ncb0505-445
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