Talin is a core component of the integrin adhesion complex. It is now shown that talin also regulates transcription, an activity that is apparently independent of its interaction with integrins. Talin represses the expression of Drosophila melanogaster DE-cadherin through an unknown molecular mechanism.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Nayal, A., Webb, D. J. & Horwitz, A. F. Curr. Opin. Cell Biol. 16, 94–98 (2004).
Brown, N. H. et al. Dev. Cell 3, 569–579 (2002).
Cram, E. J., Clark, S. G. & Schwarzbauer, J. E. J. Cell Sci. 116, 3871–3878 (2003).
Jiang, G., Giannone, G., Critchley, D. R., Fukumoto, E. & Sheetz, M. P. Nature 424, 334–337 (2003).
Bécam, I. E., Tanentzapf, G., Lepesant, J.-A., Brown, N. H. & Huynh, J.-R. Nature Cell Biol. 7, 510–516 (2005).
Gonzalez-Reyes, A. & St. Johnston, D. Science 266, 639–642 (1994).
Godt, D. & Tepass, U. Nature 395, 387–391 (1998).
Gonzalez-Reyes, A. & St. Johnston, D. Development 125, 3635–3644 (1998).
Oda, H. & Tsukita, S. Dev. Biol. 216, 406–422 (1999).
Pacquelet, A., Lin, L. & Rorth, P. J. Cell Biol. 160, 313–319 (2003).
Torres, I. L., Lopez-Schier, H. & St. Johnston, D. Dev. Cell 5, 547–558 (2003).
Lopez-Schier, H. Bioessays 25, 781–791 (2003).
Balda, M. S. & Matter, K. Trends Cell Biol. 13, 310–318 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tepass, U., Godt, D. Talin's second persona. Nat Cell Biol 7, 443–444 (2005). https://doi.org/10.1038/ncb0505-443
Issue Date:
DOI: https://doi.org/10.1038/ncb0505-443
This article is cited by
-
Regulation of Intracellular Structural Tension by Talin in the Axon Growth and Regeneration
Molecular Neurobiology (2016)