Proteins exit the trans-Golgi network (TGN) through multiple mechanisms that are poorly understood. New work identifies FAPP1 and FAPP2 as TGN-localized proteins that regulate post-Golgi carrier formation through interactions with phosphatidylinositol 4-phosphate (PtdIns(4)P) and ARF1.
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Roth, M. New candidates for vesicle coat proteins. Nat Cell Biol 6, 384–385 (2004). https://doi.org/10.1038/ncb0504-384
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DOI: https://doi.org/10.1038/ncb0504-384
