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A new member of an old family

Abstract

A newly discovered platelet-derived growth factor (PDGF) isoform, PDGF-CC, is expressed in the mouse kidney during development, at a time and location distinct from those of the other two known PDGFs. These findings, as well as the biochemical characterization of PDGF-CC, indicate that it may represent a new ligand for the PDGF α-receptor.

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Figure 1: The PDGF family.
Figure 2: PDGF-CC activation.

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Correspondence to Andrius Kazlauskas.

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Kazlauskas, A. A new member of an old family. Nat Cell Biol 2, E78–E79 (2000). https://doi.org/10.1038/35010508

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