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Diffusional protein transport within the nucleus: a message in the medium

Abstract

The movement of proteins within the nucleus can occur by diffusion, with surprisingly extensive and rapid turnover occurring in high-affinity intranuclear compartments. The transport of the proteins so far investigated does not seem to be impeded by structural elements within the interchromatin space.

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Figure 1: Diffusional movement of protein molecules in the interchromosome space.

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Correspondence to Thoru Pederson.

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Pederson, T. Diffusional protein transport within the nucleus: a message in the medium . Nat Cell Biol 2, E73–E74 (2000). https://doi.org/10.1038/35010501

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