News & Views | Published:

Double JMY: making actin fast

Nature Cell Biology volume 11, pages 375376 (2009) | Download Citation

Subjects

The assembly of actin networks is dependent on nucleation-promoting factors. A new study identifies JMY as a protein containing two separate nucleation-promoting activities that shuttles between the nucleus and the cytoplasm and promotes cell migration. These observations indicate that JMY is an important factor controlling actin dynamics in motile cells.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    & Curr. Opin. Cell Biol. 21 (1), 28–37 (2009).

  2. 2.

    , , & Cell 134, 148–161 (2008).

  3. 3.

    et al. PLoS Genet. 3, e237 (2007).

  4. 4.

    , , & Nature 433, 382–388 (2005).

  5. 5.

    , , , & Nature Cell Biol. 11, 451–459 (2009).

  6. 6.

    et al. Mol. Cell 4, 365–376 (1999).

  7. 7.

    FEBS Lett. 582, 2033–2040 (2008).

  8. 8.

    , , & EMBO Rep. 8, 84–90 (2007).

  9. 9.

    & Dev. Cell 11, 601–612 (2006).

Download references

Author information

Affiliations

  1. David W. Roadcap and James E. Bear are at the Lineberger Comprehensive Cancer Center and Department of Cell & Developmental Biology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina 27599, USA.  jbear@email.unc.edu

    • David W. Roadcap
    •  & James E. Bear

Authors

  1. Search for David W. Roadcap in:

  2. Search for James E. Bear in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/ncb0409-375

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing