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Telomeric RNA enters the game

Nature Cell Biology volume 10, pages 113–115 (2008)Cite this article

Two studies report expression of telomeric-repeat-containing RNAs in vertebrates. This discovery challenges the long-standing notion that telomeres are transcriptionally inert.

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Figure 1: Models for telomeric repeat-containing RNA (TERRA) synthesis and telomere association.

References

  1. Gilson, E. & Geli, V. Nature Rev. Mol. Cell Biol. 8, 825–838 (2007).

    Article  CAS  Google Scholar 

  2. Maizels, N. Nature Struct. Mol. Biol. 13, 1055–1059 (2006).

    Article  CAS  Google Scholar 

  3. Blasco, M. A. Nature Rev. Genet. 8, 299–309 (2007).

    Article  CAS  PubMed  Google Scholar 

  4. Baur, J. A., Zou, Y., Shay, J. W. & Wright, W. E. Science 292, 2075–2077 (2001).

    Article  CAS  PubMed  Google Scholar 

  5. Koering, C. E. et al. EMBO Rep. 3, 1055–1061 (2002).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. de Lange, T. Genes Dev. 19, 2100–2110 (2005).

    Article  CAS  PubMed  Google Scholar 

  7. Azzalin, C. M., Reichenbach, P., Khoriauli, L., Giulotto, E. & Lingner, J. Science 318, 798–801 (2007).

    Article  CAS  PubMed  Google Scholar 

  8. Schoeftner, S. & Blasco, M. A. Nature Cell Biol. 10, 228–236 (2008).

    Article  CAS  PubMed  Google Scholar 

  9. Reichenbach, P. et al. Curr. Biol. 13, 568–574 (2003).

    Article  CAS  PubMed  Google Scholar 

  10. Buhler, M. & Moazed, D. Nature Struct. Mol. Biol. 14, 1041–1048 (2007).

    Article  Google Scholar 

  11. Ciaudo, C. et al. PLoS Genet. 2, e94 (2006).

    Article  PubMed  PubMed Central  Google Scholar 

  12. Jolly, C. et al. J. Cell Biol. 164, 25–33 (2004).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Redon, S., Reichenbach, P. & Lingner, J. Nucleic Acids Res. 35, 7011–7022 (2007).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Ishikawa, F., Matunis, M. J., Dreyfuss, G. & Cech, T. R. Mol. Cell Biol. 13, 4301–4310 (1993).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Sacca, B., Lacroix, L. & Mergny, J. L. Nucleic Acids Res. 33, 1182–1192 (2005).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Cheng, J. et al. Science 308, 1149–1154 (2005).

    Article  CAS  PubMed  Google Scholar 

  17. Wyers, F. et al. Cell 121, 725–737 (2005).

    Article  CAS  PubMed  Google Scholar 

  18. Steinmetz, E. J. et al. Mol. Cell 24, 735–746 (2006).

    Article  CAS  PubMed  Google Scholar 

  19. Rassoulzadegan, M. et al. Nature 441, 469–474 (2006).

    Article  CAS  PubMed  Google Scholar 

Download references

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  1. Béatrice Horard and Eric Gilson are at the Laboratory of Molecular Biology of the Cell, ENS Lyon, CNRS UMR5239, IFR128, Faculté de Médecine Lyon Sud, Université Lyon 1, 69495 Pierre Bénite, Lyon, France. Eric.Gilson@ens-lyon.fr,

    Béatrice Horard & Eric Gilson

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  1. Béatrice Horard
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  2. Eric Gilson
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Horard, B., Gilson, E. Telomeric RNA enters the game. Nat Cell Biol 10, 113–115 (2008). https://doi.org/10.1038/ncb0208-113

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