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Expanding dynamin: from fission to fusion

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How cells maintain the balance between membrane fission and fusion is not known. Recent results show that Vps1p, a yeast dynamin-like protein, is involved in both processes at the vacuole, indicating that these two antagonistic reactions might be connected after all.

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Figure 1: Domain structure of dynamin and Vps1p.
Figure 2: Complexes involved in vacuole fusion.