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Tensions divide

Nature Cell Biology volume 12, pages 5–7 (2010)Cite this article

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During development, proliferating cells are organized into compartments with boundaries across which cells fail to intermix. Compartment boundaries are often attributed to differential cell–cell adhesion between separate compartments. However, tension generated by actomyosin cables at boundaries can also function as a barrier that prevents cell mixing.

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Figure 1: Mechanisms that establish compartment boundaries during development.

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Authors and Affiliations

  1. Department of Molecular Biology, Adam C. Martin and Eric F. Wieschaus are at the Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA. efw@princeton.edu; am5@princeton.edu,

    Adam C. Martin & Eric F. Wieschaus

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  1. Adam C. Martin
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  2. Eric F. Wieschaus
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Martin, A., Wieschaus, E. Tensions divide. Nat Cell Biol 12, 5–7 (2010). https://doi.org/10.1038/ncb0110-5

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