The spatial and temporal regulation of motor-based transport is essential to ensure precise cargo delivery in all cell types. New light has been shed on mechanisms controlling cargo–motor interactions, with the finding that NMDA-cargo is released from KIF17 kinesin following motor phosphorylation by CaMKII near the synapse.
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Ally, S., Jolly, A. & Gelfand, V. Motor-cargo release: CaMKII as a traffic cop. Nat Cell Biol 10, 3–5 (2008). https://doi.org/10.1038/ncb0108-3
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DOI: https://doi.org/10.1038/ncb0108-3