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Strabismus comes into focus

Nature Cell Biology volume 4, pages E6–E8 (2002)Cite this article

At least one member of the Frizzled (Fz) family of receptors, together with the downstream signalling protein Dishevelled, participates in several distinct, yet closely related signal transduction pathways. Activation of the correct signal transduction pathway is critical. Here, a new study suggests that the transmembrane protein Strabismus participates in this decision.

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Figure 1: Two alternative Wnt signalling pathways.
Figure 2: Planar cell polarity and convergent extension.

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  1. Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, CA 94305-5324, Stanford, USA

    Jeffrey D. Axelrod

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  1. Jeffrey D. Axelrod
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Axelrod, J. Strabismus comes into focus. Nat Cell Biol 4, E6–E8 (2002). https://doi.org/10.1038/ncb0102-e6

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