Feature | Published:

The new antibiotics

Nature Biotechnologyvolume 17pages11651169 (1999) | Download Citation

Subjects

Abstract

Can novel antibacterial treatments combat the rising tide of drug-resistant infections?

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Hancock, R.E.W. & Knowles, D. Are we approaching the end of the antibiotic era? Curr. Opin. Microbiol. 1, 493–494 (1998).

  2. 2

    http://www.phrma.org/.

  3. 3

    Strohl, W.R. (ed.) Biotechnology of antibiotics. (Marcel Dekker, New York, NY; 1997).

  4. 4

    Choudhury, D. et al. X-ray structure of the FimC–FimH chaperone–adhesin complex from uropathogenic Escherichia coli. Science 285, 1061–1066 (1999).

  5. 5

    Ganz T. & Lehrer R.I. Antimicrobial peptides of vertebrates. Curr. Opin. Immunol. 10, 41– 44 (1998).

  6. 6

    Valdovoa, R.H. & Falkow, S. Fluorescence-based isolation of bacterial genes expressed within host cells. Science 277, 2007–2011 (1997).

  7. 7

    Wilson, M. et al. Exploring drug-induced alteration in gene expression in Mycobacterium tuberculosis by microarray hybridization. Proc. Natl. Acad. Sci. USA 96, 12833–12838 (1999).

  8. 8

    Davies, J. Inactivation of antibiotics and the dissemination of resistance genes. Science 264, 375–382 ( 1994).

  9. 9

    Harvey, J. & Mason, L. The use and misuse of antibiotics in agriculture. Part 1. Current usage. (Soil Association, Bristol, UK; 1998).

Download references

Author information

Affiliations

    • Holger Breithaupt

Authors

  1. Search for Holger Breithaupt in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/70705

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing