Table 1 MDDR activity classes resembling MDDR “Dihydrofolate Reductase Inhibitor”

From: Relating protein pharmacology by ligand chemistry

Rank Activity class E-value Example molecule
1 DHFR inhibitor 7.07 × 10−182  
2 Glycinamide ribonucleotide formyltransferase inhibitor 3.97 × 10−100  
3 Folylpolyglutamate synthetase inhibitor 4.59 × 10−62  
4 TS inhibitor 1.11 × 10−61