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The obviousness rejection as a barrier to biotech patent prosecution

Nature Biotechnology volume 27, pages 11251126 (2009) | Download Citation


An analysis of US Federal Circuit decisions shows the effects of the Supreme Court's decision in KSR v. Teleflex.

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  1. 1.

    Ruiz v. A.B. Chance Co. 234 F.3d 654 (Fed. Cir. 2000).

  2. 2.

    In re Dembiczak 175 F3.d 994 (Fed. Cir. 1999).

  3. 3.

    In re Kotzab 217 F.3d 1365, 1371 (Fed. Cir. 2000).

  4. 4.

    KSR Int'l Co. v. Teleflex, Inc. 550 US 398 (2007).

  5. 5.

    & Nat. Biotechnol. 27, 446–448 (2009).

  6. 6.

    Takeda Chem. Indus., Ltd. v. Alphapharm Pty., Ltd. 492 F.3d 1350 (Fed. Cir. 2007).

  7. 7.

    Pharmastem Therapeutics, Inc. v. Viacell, Inc., et al. 491 F.3d 1342 (Fed. Cir. 2007).

  8. 8.

    In re Kubin __ F.3d __, No. 2008-1184 (Fed. Cir. 2009).

  9. 9.

    Pfizer, Inc. v. Apotex, Inc. 480 F.3d 1348 (Fed. Cir. 2007).

  10. 10.

    In re Peterson 315 F.3d 1325 (Fed. Cir. 2003).

  11. 11.

    WMS Gaming, Inc. v. Int'l Game Tech. 184 F.3d 1339 (Fed. Cir. 1999).

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This study was supported by the National Science Council, Taiwan, Republic of China (grant no. NSC 96-2414-H-075-001), Taipei Veterans General Hospital project (V98C1-190) and Committee on Chinese Medicine and Pharmacy (CCMP97-RD-117). The author would also like thank I.T. Huang, for summarizing the CAFC ruling and H.C. Lee for the statistical analysis.

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  1. Shyh-Jen Wang is in the Division of Experimental Surgery, Department of Surgery, Taipei Veterans General Hospital and the Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan, Republic of China.

    • Shyh-Jen Wang


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Correspondence to Shyh-Jen Wang.

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