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Knocking the SOCS1 off dendritic cells

siRNA-mediated inhibition of SOCS1 function enhances the immunostimulatory capacity of dendritic cells and may lead to more effective cancer vaccines.

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Figure 1: Regulation of dendritic cell differentiation into immunostimulatory antigen-presenting cells.

Bob Crimi

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Gilboa, E. Knocking the SOCS1 off dendritic cells. Nat Biotechnol 22, 1521–1522 (2004). https://doi.org/10.1038/nbt1204-1521

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