I will discuss the uses of science advice in forming government policies on questions that involve emerging technology. In particular, I will review the UK Guidelines on Science Advice and Policy Making with their emphasis on wide consultation and openness. I will share some personal thoughts on the opportunities and difficulties associated with such open dialogue between policy makers and the public—or many different “publics”—especially when many different viewpoints contend. Much of this discussion will, of course, focus on present and likely future prospectives on agriculture, food, and the environment.