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Boolean calculations made easy (for ribozymes)

Nature Biotechnology volume 23, pages 1374–1376 (2005)Cite this article

A new algorithm facilitates the design of ribozymes that encode logical operations.

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Figure 1: a, Schematic representation of an AND gate with the hammerhead ribozyme structural motif.

Bob Crimi

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Authors and Affiliations

  1. Department of Biomedical Informatics and the Joint Centers for Systems Biology, Columbia University, 1130 St. Nicholas Ave., New York, 10032, New York, USA

    Adam A Margolin

  2. NSF Center for Molecular Cybernetics and the Division of Experimental Therapeutics, Department of Medicine, Columbia University, 650 W. 168th St., New York, 10032, New York, USA

    Milan N Stojanovic

Authors
  1. Adam A Margolin
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  2. Milan N Stojanovic
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Margolin, A., Stojanovic, M. Boolean calculations made easy (for ribozymes). Nat Biotechnol 23, 1374–1376 (2005). https://doi.org/10.1038/nbt1105-1374

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