Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

A Novel Approach to Bioassays

Bio/Technology volume 6, pages 1169–1172 (1988)Cite this article

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Familletti, P.G., Rubinstein, S., and Pestka, S. 1981. A convenient and rapid cytopathic effect inhibition assay for interferon. Methods Enzymol. 78:387.

    Article  CAS  Google Scholar 

  2. Gillis, S., Ferm, M.M., Ou, W., and Smith, K.A. 1978. T-cell growth factor: parameters of production and a quantitative microassay for activity. J. Immun. 120:2027.

    CAS  Google Scholar 

  3. Mizel, S.B., Oppenheim, J.J., and Rosenstreich, D.L. 1978. Characterization of lym phocyte-activating factor (LAP) produced by the macrophage cell line P388D. J. Immun. 120:1497.

    CAS  PubMed  Google Scholar 

  4. Rubinstein, S., Familletti, P.G., and Pestka, S. 1981. Convenient assay for interferons. Journ. Virol. 37:755.

    CAS  Google Scholar 

  5. Evinger, M., Maeda, S. and Pestka, S. 1980. Recombinant human leukocyte interferon produced in bacteria has antiproliferative activity. J. Biol. Chem. 256:2113.

    Google Scholar 

  6. Inoue, M., and Tan, Y.H. 1981. Radioimmunoassay for human beta interferon. Infect. Immun. 33:763.

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Budd, R.C., and Smith, K.A. 1986. Immunoassay using monoclonal antibodies. Bio/Technology 4:983.

    Article  CAS  Google Scholar 

  8. Mosmann, T. 1983. Rapid colorimetric as say for cellular growth and survival: application to proliferation and cytotoxicity as says. J. Immun. Methods. 65:55.

    Article  CAS  Google Scholar 

  9. Yeh, T.-J., McBride, P.T., Overall, J.C., and Green, J.A. 1982. Automated quantita tive cytopathic effect reduction assay for interferon. J. Clinical Micro. 16:413.

    CAS  Google Scholar 

  10. Tada, H., Shiho, O., Kuroshima, K.-I., Moyama, M., and Tsukamoto, K. 1986. An improved colorimetric assay for interleukin-2. J. Immun. Methods. 93:157.

    Article  CAS  Google Scholar 

  11. Schmidt, J.A., Mizel, S.B., Cohen, D., and Green, L. 1982. Interleukin-1, a potential regulator of fibroblast proliferation. J. Immun. 128:2177.

    CAS  PubMed  Google Scholar 

  12. Gehman, L.O. and Robb, R.J. 1984. An ELISA-based assay for quantitation of human interleukin-2. J. Immunol. Methods. 74:39.

    Article  CAS  Google Scholar 

  13. Nachlas, M.M., Stanley, M.I., Goldberg, J.D., and Seligman, A.M. 1960. The determination of lactic acid dehydrogenase with a tetrazolium salt. Anal. Biochem. 1:317.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Molecular Genetics, HoffmannLa Roche, Inc., Nutley, NJ, 07110

    Philip C. Familletti & Judith A. Wardwell-Swanson

Authors
  1. Philip C. Familletti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Judith A. Wardwell-Swanson
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Familletti, P., Wardwell-Swanson, J. A Novel Approach to Bioassays. Nat Biotechnol 6, 1169–1172 (1988). https://doi.org/10.1038/nbt1088-1169

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt1088-1169

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing