MicroRNAs and cancer stem cells continue to dominate the list of most-cited papers, but the biotech paper that made the biggest splash was the first description of induced pluripotent stem (iPS) cells. Despite the emergence of the latter area, publications on embryonic stem cells as a whole contracted in 2007, and proteomics and RNA interference tailed off. The number of papers in nanotech and systems biology continued to expand rapidly. China overtook the United States for the first time in terms of output of 'biotech' papers.
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Taroncher-Oldenburg, G., Marshall, A. Trends in biotech literature 2007. Nat Biotechnol 26, 1062 (2008). https://doi.org/10.1038/nbt1008-1062