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Can complexity be commercialized?

Big pharma is dabbling in systems biology, a few brave entrepreneurs are trying to make a business out of it, but investor caution may keep those in the field from really making it big in drug development.

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Figure 1: Top-down versus bottom-up approaches.
Figure 2: Cell cycle model showing G1-S transition and the highly connected p53 node.
Figure 3: Beyond Genomics Correlation Network: Up- and downregulated genes, proteins and metabolites in a mammalian disease model versus controls ('normals').


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Mack, G. Can complexity be commercialized?. Nat Biotechnol 22, 1223–1229 (2004).

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