Carbohydrates play a wide range of important roles in the body and, despite the challenges posed by glycobiology, are now tempting targets for drug developers.
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References
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Barton, W.A. et al. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nat. Struct. Biol. 8, 545–551 (2001).
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Dove, A. The bittersweet promise of glycobiology. Nat Biotechnol 19, 913–917 (2001). https://doi.org/10.1038/nbt1001-913
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DOI: https://doi.org/10.1038/nbt1001-913
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