Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Biotools
  • Published:

Affinity Fingerprinting

Bio/Technology volume 13, pages 965–966 (1995)Cite this article

A novel approach to quantitative chemical classification proves useful in drug discovery

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Kenan, D.J., Tsai, D.E., and Keene, J.D. 1994. Exploring molecular diversity with combinatorial shape libraries. Trends in Biochem. Sci. 19: 57–64.

    Article  CAS  Google Scholar 

  2. LaBella, F.S. 1991. Molecular basis for binding promiscuity of antagonist drugs. Biochem. Pharm. 42: 51–58.

    Article  Google Scholar 

  3. Kauvar, L.M. 1994. Method to identify drug candidates. U.S. Patent No. 5,300,425.

  4. Kauvar, L.M., Higgins, D.L., Villar, H.O., Sportsman, J.R., Engqvist-Goldstein, R., Bukar, K.E., Bauer, H. and Rocke, D.M. 1995. Predicting ligand binding to proteins by affinity fingerprinting. Chem. & Biol. 2: 107–118.

    Article  CAS  Google Scholar 

  5. Kauvar, L.M. 1995. Toxic chemical detection by pattern recognition. In: New Frontiers in Agrochemical Immunoassay, (D. Kurtz, L. Stanker, and J.H. Skerritt, eds.). Washington, D.C.: AOAC, in press.

    Google Scholar 

  6. Kauvar, L.M. 1995. Affinity fingerprinting: an index to chemical variety. Pharm. Mfr. Intl. 8: 25–28.

    Google Scholar 

  7. Kauvar, L.M. 1994. Panels of analyte-binding ligands. U.S. Patent No. 5,340,474.

  8. Villar, H.O. and Kauvar, L.M. 1994. Amino acid preferences at protein binding sites. FEBS Letters 349: 125–130.

    Article  CAS  Google Scholar 

  9. Mitchison, T.J. 1994. Towards a pharmacological genetics. Chem. & Biol. 1: 3–6.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. vice president and chief scientist at Terrapin Technologies, Inc., 750-H Gateway Blvd., S., San Francisco, CA, 94080

    Lawrence M. Kauvar

Authors
  1. Lawrence M. Kauvar
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kauvar, L. Affinity Fingerprinting. Nat Biotechnol 13, 965–966 (1995). https://doi.org/10.1038/nbt0995-965

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0995-965

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing