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Reshaping pluripotent stem cells

Engineered zinc-finger nucleases are used to generate several genetically modified pluripotent stem cell lines.

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Figure 1: Comparison of the protocols for the genetic modification of human pluripotent stem cells by conventional or ZFN-facilitated homologous recombination.

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Correspondence to Andrew G Elefanty.

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Elefanty, A., Stanley, E. Reshaping pluripotent stem cells. Nat Biotechnol 27, 823–824 (2009). https://doi.org/10.1038/nbt0909-823

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