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Silencing prostate cancer

Systemic delivery of an siRNA–aptamer chimera leads to prostate cancer regression in mice.

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Figure 1: Strategies for systemic delivery of siRNA.

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Correspondence to Antonin de Fougerolles.

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Competing interests

A.D.F. and I.T. are employees of Alnylam Pharmaceuticals, a company engaged in the development of RNAi therapeutics.

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Toudjarska, I., de Fougerolles, A. Silencing prostate cancer. Nat Biotechnol 27, 821–823 (2009). https://doi.org/10.1038/nbt0909-821

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