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Keeping dry and crossing membranes

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Figure 1: Wrapping of the glucagon molecule in helical conformation (PDB entry 1GCN).
Figure 2: Time dependence of the adsorption uptake and desorption of soluble mutants of the G4V glucagon peptide onto and from a dilauryl phosphatidylcholine bilayer coating a biosensing optical device.

Bob Crimi


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This research was supported in part by an unrestricted grant from Eli Lilly and Company. The work was motivated by conversations with Richard DiMarchi.

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Fernández, A. Keeping dry and crossing membranes. Nat Biotechnol 22, 1081–1084 (2004).

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