Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Transgenesis sunny-side up

The use of primordial germ cells to transmit genetic modifications through the chicken germ line is a significant advance for avian biology.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Production of transgenic chickens using cultured PGCs.

Katie Ris

References

  1. Lillico, S. et al. Drug Discov. Today 10, 191–196 (2005).

    Article  CAS  Google Scholar 

  2. van de Lavoir, M.C. et al. Nature 441, 766–769 (2006).

    Article  CAS  Google Scholar 

  3. Sang, H. Mech. Dev. 121, 1179–1186 (2004).

    Article  CAS  Google Scholar 

  4. McGrew, M.J. et al. EMBO Rep. 5, 728–733 (2004).

    Article  CAS  Google Scholar 

  5. Petitte, J.N. et al. Development 108, 185–189 (1990).

    CAS  PubMed  Google Scholar 

  6. Pain, B. et al. Development 122, 2339–2348 (1996).

    CAS  PubMed  Google Scholar 

  7. van de Lavoir, M.C. et al. Mech. Dev. 123, 31–41 (2006).

    Article  CAS  Google Scholar 

  8. D'Costa, S. et al. Avian Poultry Biol. Rev. 12, 151–168 (2001).

    Article  Google Scholar 

  9. Zhu, L. et al. Nat. Biotechnol. 23, 1159–1169 (2005).

    Article  CAS  Google Scholar 

  10. Rapp, J.C. et al. Transgenic Res. 12, 569–575 (2003).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sang, H. Transgenesis sunny-side up. Nat Biotechnol 24, 955–956 (2006). https://doi.org/10.1038/nbt0806-955

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0806-955

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing