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Discovering DNA regulatory elements with bacteria

A bacterial one-hybrid selection system offers a low-tech alternative for determining the DNA-binding specificities of transcription factors.

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Figure 1: The bacterial one-hybrid system of Meng et al.

Bob Crimi

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Bulyk, M. Discovering DNA regulatory elements with bacteria. Nat Biotechnol 23, 942–944 (2005). https://doi.org/10.1038/nbt0805-942

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  • DOI: https://doi.org/10.1038/nbt0805-942

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