A bacterial one-hybrid selection system offers a low-tech alternative for determining the DNA-binding specificities of transcription factors.
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References
Meng, X., Brodsky, M.H. & Wolfe, S.A. Nat. Biotechnol. 23, 995–1001 (2005).
Dove, S.L., Joung, J.K. & Hochschild, A. Nature 386, 627–630 (1997).
Iyer, V.R. et al. Nature 409, 533–538 (2001).
Lieb, J.D., Liu, X., Botstein, D. & Brown, P.O. Nat. Genet. 28, 327–334 (2001).
Ren, B. et al. Science 290, 2306–2309 (2000).
Oliphant, A.R., Brandl, C.J. & Struhl, K. Mol. Cell. Biol. 9, 2944–2949 (1989).
Mukherjee, S. et al. Nat. Genet. 36, 1331–1339 (2004).
Wilson, T.E., Fahrner, T.J., Johnston, M. & Milbrandt, J. Science 252, 1296–1300 (1991).
Joung, J.K., Ramm, E.I. & Pabo, C.O. Proc. Natl. Acad. Sci. USA 97, 7382–7387 (2000).
Velculescu, V.E., Zhang, L., Vogelstein, B. & Kinzler, K.W. Science 270, 484–487 (1995).
Messina, D.N., Glasscock, J., Gish, W. & Lovett, M. Genome Res. 14, 2041–2047 (2004).
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Bulyk, M. Discovering DNA regulatory elements with bacteria. Nat Biotechnol 23, 942–944 (2005). https://doi.org/10.1038/nbt0805-942
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DOI: https://doi.org/10.1038/nbt0805-942
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