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Proteomics retrenches

Nature Biotechnology volume 28, pages 665–670 (2010)Cite this article

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Improvements in technology are making proteomics research less descriptive and more analytic, but the field has yet to deliver on its aspirations.

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Figure 1: The dynamic range of plasma proteins.
Figure 2: Missing the mark.
Figure 3: The relationship between tandem MS (MS/MS) and multiple reaction monitoring (MRM).

References

  1. Wright, C. et al. Mol. Cell. Proteomics published online, doi:10.1074/mcp.M900384-MCP200 (1 February 2010).

  2. Anderson, K.S. et al. Cancer Epidemiol. Biomarkers Prev. 19, 859–868 (2010).

    Article  CAS  Google Scholar 

  3. Mann, M. Nat. Methods 6, 717–719 (2009).

    Article  CAS  Google Scholar 

  4. Bell, A.W. et al. Nat. Methods 6, 423–430 (2009).

    Article  CAS  Google Scholar 

  5. Paulovich, A.G. et al. Mol. Cell. Proteomics 9, 242–254 (2010).

    Article  CAS  Google Scholar 

  6. Adonna, T.A. et al. Nat. Biotechnol. 27, 633–641 (2009).

    Article  Google Scholar 

  7. McIntosh, M. & Fitzgibbon, M. Nat. Biotechnol. 27, 622–623 (2009).

    Article  CAS  Google Scholar 

  8. Zielinska, D.F. et al. Cell 141, 897–907 (2010).

    Article  CAS  Google Scholar 

  9. Lee, A.Y.H. et al. J. Proteome Res. 7, 5177–5186 (2008).

    Article  CAS  Google Scholar 

  10. de Godoy, L.M. et al. Nature 455, 1251–1254 (2008).

    Article  CAS  Google Scholar 

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  1. Peter Mitchell is a freelance writer based in London.,

    Peter Mitchell

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Mitchell, P. Proteomics retrenches. Nat Biotechnol 28, 665–670 (2010). https://doi.org/10.1038/nbt0710-665

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