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Minicells overcome tumor drug-resistance

Bacterially derived minicells loaded with siRNA reverse drug resistance in tumor xenografts.

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Figure 1: Bacterially derived minicells can deliver siRNA and plasmid-encoded shRNA to reverse tumor drug resistance in vivo.

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Correspondence to Daniel G Anderson.

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Karagiannis, E., Anderson, D. Minicells overcome tumor drug-resistance. Nat Biotechnol 27, 620–621 (2009). https://doi.org/10.1038/nbt0709-620

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