A method for amplifying DNA from single bacterial cells shows promise for complete genome sequencing.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
Nature Biotechnology Open Access 01 August 2017
-
Improved genome recovery and integrated cell-size analyses of individual uncultured microbial cells and viral particles
Nature Communications Open Access 20 July 2017
-
Impact of library preparation protocols and template quantity on the metagenomic reconstruction of a mock microbial community
BMC Genomics Open Access 24 October 2015
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Bob Crimi
References
Zhang, K. et al. Nat. Biotechnol. 24, 681–687 (2006).
Dean, F.B., Nelson, J.R., Giesler, T.L. & Lasken, R.S. Genome Res. 11, 1095–1099 (2001).
Dean, F.B. et al. Proc. Natl. Acad. Sci. USA 99, 5261–5266 (2002).
Lizardi, P.M. et al. Nat. Genet. 19, 225–232 (1998).
Raghunathan, A. et al. Appl. Environ. Microbiol. 71, 3342–3347 (2005).
Hutchison, C.A., III, Smith, H.O., Pfannkoch, C. & Venter, J.C. Proc. Natl. Acad. Sci. USA 102, 17332–17336 (2005).
Margulics, M. et al. Nature 437, 376–380 (2005).
Hughes, S. & Lasken, R. (eds.) Whole Genome Amplification (Scion Publishing Ltd., Bloxham, Oxfordshire, UK, 2005).
Venter, J.C. et al. Science 304, 66–74 (2004).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hutchison, C., Venter, J. Single-cell genomics. Nat Biotechnol 24, 657–658 (2006). https://doi.org/10.1038/nbt0606-657
Issue Date:
DOI: https://doi.org/10.1038/nbt0606-657
This article is cited by
-
Testing culture purity in prokaryotes: criteria and challenges
Antonie van Leeuwenhoek (2018)
-
Improved genome recovery and integrated cell-size analyses of individual uncultured microbial cells and viral particles
Nature Communications (2017)
-
Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
Nature Biotechnology (2017)
-
Impact of library preparation protocols and template quantity on the metagenomic reconstruction of a mock microbial community
BMC Genomics (2015)
-
Genomic Mining for Novel FADH2-Dependent Halogenases in Marine Sponge-Associated Microbial Consortia
Marine Biotechnology (2013)
