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Sweet surrender to chemical genetics

Nature Biotechnology volume 20, pages 561563 (2002) | Download Citation

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Small molecules can extend the resolution of functional genomics beyond gene knockouts, allowing specific functions of a multifunctional protein to be modulated selectively.

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Affiliations

  1. Derek S. Tan is head of the Laboratory of Chemistry & Chemical Genetics and an assistant member at the Memorial Sloan–Kettering Cancer Center, 1275 York Ave., RRL-1317, Box 422, New York, NY 10021 tand@mskcc.org.

    • Derek S. Tan

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DOI

https://doi.org/10.1038/nbt0602-561

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