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Sweet surrender to chemical genetics

Nature Biotechnology volume 20, pages 561–563 (2002)Cite this article

Small molecules can extend the resolution of functional genomics beyond gene knockouts, allowing specific functions of a multifunctional protein to be modulated selectively.

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Figure 1: Discovery and analysis of uretupamine A and B.

© Bob Crimi

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  1. head of the Laboratory of Chemistry & Chemical Genetics and an assistant member at the Memorial Sloan–Kettering Cancer Center, 1275 York Ave., RRL-1317, Box 422, New York, 10021, NY

    Derek S. Tan

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  1. Derek S. Tan
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Tan, D. Sweet surrender to chemical genetics. Nat Biotechnol 20, 561–563 (2002). https://doi.org/10.1038/nbt0602-561

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