Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Boning up on telomerase

The expression of telomerase in bone marrow stromal cells brings cell-based bone tissue engineering one step closer to reality.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Telomerase expression extends the life-span and enhances the osteogenic potential of mesenchymal progenitor cells derived from human bone marrow stroma.

© Bob Crimi

References

  1. Bruder, S.P. et al. J. Cell. Biochem. 64, 278–294 (1997).

    Article  CAS  Google Scholar 

  2. Simonsen, J.L. et al. Nat. Biotechnol. 20, 592–596 (2002).

    Article  CAS  Google Scholar 

  3. Shi, S. et al. Nat. Biotechnol. 20, 587–591 (2002).

    Article  CAS  Google Scholar 

  4. Caplan, A.I. & Bruder, S.P. Trends Mol. Med. 7, 259–264 (2001).

    Article  CAS  Google Scholar 

  5. Grainger, M.P. et al. Crit. Rev. Oncol. Hematol. 41, 29–40 (2002).

    Article  Google Scholar 

  6. Nishida, S. et al. J. Bone Miner. Res. 17, 171–177 (1999).

    Article  CAS  Google Scholar 

  7. Toma, J.G. et al. Nat. Cell Biol. 3, 778–784 (2001).

    Article  CAS  Google Scholar 

  8. Lee, J.Y. et al. J. Cell Bio. 150, 1085–1100 (2000).

    Article  CAS  Google Scholar 

  9. Erickson, G. et al. Biochem. Biophys. Res. Commun. 290, 763–769 (2002).

    Article  CAS  Google Scholar 

  10. Noth, U. et al. J. Orthop. Res. in press (2002).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tuan, R. Boning up on telomerase. Nat Biotechnol 20, 560–561 (2002). https://doi.org/10.1038/nbt0602-560

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0602-560

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing