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Viral Protection in Transgenic Tobacco Plants Expressing the Cucumber Mosaic Virus Coat Protein or its Antisense RNA

Bio/Technology volume 6, pages 549–557 (1988)Cite this article

A Corrigendum to this article was published on 01 July 2009

Abstract

Progeny of transgenic tobacco plants expressing the cucumber mosaic virus (CMV) coat protein (CP +) or its antisense transcript (antisense–CP) were protected from CMV infection. Symptom development and virus accumulation were reduced or absent in CP+ plants, independent of the strength of the inoculum. Antisense–CP plants were protected only at low inoculum concentrations. These results demonstrate that although it is possible to obtain protection in transgenic plants using antisense–CP message, this protection is not as effective as the CP–mediated protection.

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Author notes

  1. Maria Cuozzo, Rong-Xiang Fang and Nam-Hai Chua: Laboratory of Plant Molecular Biology, The Rockefeller University, New York, N.Y. 10021-6399.

  2. Nilgun E. Tumer: Author to whom correspondence should be addressed.

Authors and Affiliations

  1. Plant Molecular Biology, Division of Biological Sciences, Monsanto Co., 700 Chesterfield Village Parkway, St. Louis, MO, 63198

    Keith M. O'Connell, Wojciech Kaniewski & Nilgun E. Tumer

Authors
  1. Maria Cuozzo
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  2. Keith M. O'Connell
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  3. Wojciech Kaniewski
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  4. Rong-Xiang Fang
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  5. Nam-Hai Chua
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  6. Nilgun E. Tumer
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Cuozzo, M., O'Connell, K., Kaniewski, W. et al. Viral Protection in Transgenic Tobacco Plants Expressing the Cucumber Mosaic Virus Coat Protein or its Antisense RNA. Nat Biotechnol 6, 549–557 (1988). https://doi.org/10.1038/nbt0588-549

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  • DOI: https://doi.org/10.1038/nbt0588-549

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