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The impact of greed on academic medicine and patient care

Nature Biotechnology volume 26, pages 503–507 (2008)Cite this article

Abstract

To what extent is the increasing emphasis on profit generation at US academic institutions shackling intellectual freedom and compromising healthcare?

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Figure 1: The present public-private system for funding and disseminating knowledge.
Figure 2: Potential model of AMC-nonprofit primacy for the development and dissemination of certain US taxpayer–funded innovations for small market sizes.

References

  1. Pisano, G.P. Science Business: The Promise, the Reality, and the Future of Biotech (Harvard Business School Press, Boston, 2006).

    Google Scholar 

  2. Brown, L.D. N. Engl. J. Med. 358, 325–327 (2008).

    Article  CAS  Google Scholar 

  3. Sobolski, G.K., Barton, J.H. & Emanuel, E.J. J. Am. Med. Assoc. 294, 3137–3140 (2005).

    Article  CAS  Google Scholar 

  4. Yancey, A. & Stewart, C.N. Jr. Nat. Biotechnol. 25, 1225–1228 (2007).

    Article  CAS  Google Scholar 

  5. Association of University Technology Managers. FY2006 U.S. Licensing Activity Survey. <http://www.autm.org/events/file/AUTM_06_US20LSS_FNL.pdf> (2006).

  6. Frangioni, J.V. Nat. Biotechnol. 24, 909–913 (2006).

    Article  CAS  Google Scholar 

  7. KSR International Co. v. Teleflex Inc. et al. 550 U.S. 04–1350 <http://www.supremecourtus.gov/opinions/06pdf/04-1350.pdf> (2007).

  8. Ehringhaus, S.H. et al. J. Am. Med. Assoc. 299, 665–671 (2008).

    Article  CAS  Google Scholar 

  9. US Food and Drug Administration. Challenge and opportunity on the critical path to new medical products. <http://www.fda.gov/oc/initiatives/criticalpath/ whitepaper.html#execsummary> (2004).

  10. Henderson, J.A. & Smith, J.J. Academia, industry, and the Bayh-Dole Act: an implied duty to commercialize. <http://www.cimit.org/coi_part3.pdf> (2002).

  11. Wood, A.J. N. Engl. J. Med. 355, 618–623 (2006).

    Article  CAS  Google Scholar 

  12. H.R. 1908. Patent Reform Act of 2007. <http://thomas.loc.gov/cgi-bin/bdquery/z?d110:H.R.1908:> (2007).

  13. Heller, M.A. & Eisenberg, R.S. Science 280, 698–701 (1998).

    Article  CAS  Google Scholar 

  14. Association of Professors of Medicine Physician-Scientist Initiative Consensus Conference, 'Revitalization of the Nation's Physician-Scientist Workforce,' Washington, DC, 25 November 2007.

Download references

Acknowledgements

I thank M.L. Zeidel, R.E. Lenkinski, J.S. Felsch, M.D. Chalek, P.F. Levy, V. Sukhatme, J.S. Flier and M. Rosenberg for many discussions, B.L. Clough and A. Gugelmann for editing, and E. Trabucchi for administrative assistance. I especially thank C.T. Lelon for his thoughtful analysis of capitalism and S.J. Nowak III for his thoughts on profit.

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  1. John V. Frangioni is at Beth Israel Deaconess Medical Center and the Harvard Medical School, 330 Brookline Avenue, Room SL-B05, Boston, Massachusetts 02215, USA. jfrangio@bidmc.harvard.edu,

    John V Frangioni

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Frangioni, J. The impact of greed on academic medicine and patient care. Nat Biotechnol 26, 503–507 (2008). https://doi.org/10.1038/nbt0508-503

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