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Tunable antibodies

A recent Keystone meeting highlighted the progress in generating effective anti-cancer antibodies by manipulating antibody binding affinity and their ability to support ADCC.

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Figure 1: Antibody structure can be manipulated to fit an intended therapeutic application.

Bob Crimi


  1. Keystone Symposium: Antibody-based Therapeutics for Cancer, Hilton Hotel, Santa Fe, New Mexico, February 17–22, 2005.

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Weiner, L., Carter, P. Tunable antibodies. Nat Biotechnol 23, 556–557 (2005).

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