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Antagonizing metastasis

Therapeutic inhibition of a microRNA reduces metastasis formation in a mouse model of breast cancer.

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Figure 1: Antagomir treatment to prevent metastatic spread of breast cancer in mice.

Katie Vicari

References

  1. Nguyen, D.X., Bos, P.D. & Massague, J. Nat. Rev. Cancer 9, 274–284 (2009).

    Article  CAS  Google Scholar 

  2. Ma, L. et al. Nat. Biotechnol. 28, X341–347 (2010).

    Article  Google Scholar 

  3. Bartel, D.P. Cell 136, 215–233 (2009).

    Article  CAS  Google Scholar 

  4. Garzon, R., Calin, G.A. & Croce, C.M. Annu. Rev. Med. 60, 167–179 (2009).

    Article  CAS  Google Scholar 

  5. Nicoloso, M.S., Spizzo, R., Shimizu, M., Rossi, S. & Calin, G.A. Nat. Rev. Cancer 9, 293–302 (2009).

    Article  CAS  Google Scholar 

  6. Yang, J. et al. Cell 117, 927–939 (2004).

    Article  CAS  Google Scholar 

  7. Ma, L., Teruya-Feldstein, J. & Weinberg, R.A. Nature 449, 682–688 (2007).

    Article  CAS  Google Scholar 

  8. Gee, H.E. et al. Nature 455, E8–9; author reply E9 (2008).

    Article  CAS  Google Scholar 

  9. Baffa, R. et al. J. Pathol. 219, 214–221 (2009).

    Article  CAS  Google Scholar 

  10. Krutzfeldt, J. et al. Nature 438, 685–689 (2005).

    Article  Google Scholar 

  11. Brown, B.D. & Naldini, L. Nat. Rev. Genet. 10, 578–585 (2009).

    Article  CAS  Google Scholar 

  12. Husemann, Y. et al. Cancer Cell 13, 58–68 (2008).

    Article  Google Scholar 

  13. Bergers, G. & Hanahan, D. Nat. Rev. Cancer 8, 592–603 (2008).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Luigi Naldini.

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The authors declare no competing financial interests.

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De Palma, M., Naldini, L. Antagonizing metastasis. Nat Biotechnol 28, 331–332 (2010). https://doi.org/10.1038/nbt0410-331

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