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The use of tolerance for transplantation across xenogeneic barriers

Nature Biotechnology volume 15, pages 235–238 (1997)Cite this article

Abstract

The success of human organ transplantation as a clinical treatment has created a conundrum for the transplant community. It has caused a shortage of human donor organs and uncovered problems of chronic immunosuppression in those lucky enough to receive organ transplants due to their use of chronic immunosuppressive drugs. Our aim is to attempt to approach both issues by establishing specific transplantation tolerance to pig organ grafts.

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Author notes

  1. Julia L. Greenstein: Corresponding author.

Authors and Affiliations

  1. BioTransplant Incorporated, Building 75, Third Avenue, Charlestown Navy Yard, Charlestown, MA, 02129

    Julia L. Greenstein

  2. Harvard Medical School and the Transplantation Biology Research Center, Massachusetts General Hospital, MGH-East, Building 149-9019, Thirteenth Street, Boston, MA, 02129

    David H. Sachs

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  1. Julia L. Greenstein
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  2. David H. Sachs
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Greenstein, J., Sachs, D. The use of tolerance for transplantation across xenogeneic barriers. Nat Biotechnol 15, 235–238 (1997). https://doi.org/10.1038/nbt0397-235

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