Interaction maps for kinase inhibitors

The specificity of kinase inhibitors can be rapidly determined with a new in vitro competition assay.

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Figure 1: A quantitative assay for measuring the binding of unlinked small molecules to the ATP-binding site of kinases.

Bob Crimi

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Griffin, J. Interaction maps for kinase inhibitors. Nat Biotechnol 23, 308–309 (2005). https://doi.org/10.1038/nbt0305-308

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